Boc-Aminooxy-PEG3-azide , ≥95% , 1235514-15-4
CAS NO.：1235514-15-4
Empirical Formula: C13H26N4O6
Molecular Weight: 334.37
MDL number: MFCD28950781
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB1280.00 | In Stock |
|
| others | Enquire |
Description and Uses
t-Boc-Aminooxy-PEG3-azide is a click chemistry reagent containing a t-Boc-aminooxy group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The protected aminooxy can be deprotected under mild acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
Boc-Aminooxy-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-Aminooxy-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
