Home Categories T-Boc-aminooxy-peg3-acid
M7441858

T-Boc-aminooxy-peg3-acid , 98% , 1835759-82-4

CAS NO.:1835759-82-4

Empirical Formula: C14H27NO8

Molecular Weight: 337.37

MDL number: MFCD29052175

Pack Size Price Stock Quantity
1g RMB8853.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Density  1.155±0.06 g/cm3(Predicted)
solubility  Soluble in Water, DMSO, DMF, DCM
pka 4.28±0.10(Predicted)

Description and Uses

t-Boc-Aminooxy-PEG3-acid is a PEG linker containing a Boc-protected aminooxy group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc-protected amine can be deprotected under mild acidic conditions.

Boc-Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

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