M7441858
T-Boc-aminooxy-peg3-acid , 98% , 1835759-82-4
Pack Size | Price | Stock | Quantity |
1g | RMB8853.60 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Density | 1.155±0.06 g/cm3(Predicted) |
solubility | Soluble in Water, DMSO, DMF, DCM |
pka | 4.28±0.10(Predicted) |
Description and Uses
t-Boc-Aminooxy-PEG3-acid is a PEG linker containing a Boc-protected aminooxy group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc-protected amine can be deprotected under mild acidic conditions.
Boc-Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].