Aminooxy-peg3-t-butylester , 95% , 1835759-72-2
Pack Size | Price | Stock | Quantity |
1g | RMB8792.00 | In Stock |
|
others | Enquire |
PRODUCT Properties
Boiling point: | 392.4±32.0 °C(Predicted) |
Density | 1.063±0.06 g/cm3(Predicted) |
pka | 4.21±0.70(Predicted) |
Description and Uses
Aminooxy-PEG3-t-butyl ester is an aminooxy-containing PEG molecule. The hydrophilic PEG spacer increases solubility in aqueous media. The aminooxy group is reactive with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The t-butyl ester can be converted tofree acid under acidic condition. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
Aminooxy-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].