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M7221858

Boc-NH-PEG4-azide , ≥95% , 940951-99-5

CAS NO.:940951-99-5

Empirical Formula: C15H30N4O6

Molecular Weight: 362.43

MDL number: MFCD28015765

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100mg RMB1280.00 In Stock
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Update time: 2022-07-08

Description and Uses

t-Boc-N-Amido-PEG4-azide is a N-Boc protected PEG reagent. It can react with alkyne, BCN, DBCO via Click Chemistry. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Boc-NH-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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