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M7237858

Purineribosidetriphosphate , ≥98% , 23197-96-8

CAS NO.:23197-96-8

Empirical Formula: C10H11N4Na4O13P3

Molecular Weight: 580.09

MDL number: MFCD04118066

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5mg RMB2400.00 In Stock
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Update time: 2022-07-08

Description and Uses

Purine riboside-5'-O-triphosphate, an active metabolite of Nebularine (HY-103694), acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 μM and 28 μM for the human enzyme, respectively. Purine riboside-5'-O-triphosphate also inhibits calmodulin-dependent protein kinase II (CaMKII) with a Ki value of 590 μM[1][2][3].

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