Home Categories Analytical Chemistry OleicAcid-13C
M8062647

OleicAcid-13C , ≥98% , 82005-44-5

CAS NO.:82005-44-5

Empirical Formula: C18H34O2

Molecular Weight: 283.47

MDL number: MFCD01073865

Pack Size Price Stock Quantity
5mg RMB2015.20 In Stock
100mg RMB12000.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 13.4 °C(lit.)
Boiling point: 192-195 °C1.2 mm Hg(lit.)
Density  0.893 g/mL at 25 °C
refractive index  n20/D 1.4595(lit.)
Flash point: >230 °F(lit.)
storage temp.  -20°C
solubility  Ethanol: 1.5 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
form  Liquid
color  Colorless to light yellow

Description and Uses

Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid (Item Nos. 90260 | 24659) by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue. It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets. Oleic acid inhibits collagen-stimulated platelet aggregation by approximately 90% when used at a concentration of 10 μg/ml. It also inhibits fMLF-induced neutrophil aggregation and degranulation by 55 and 68%, respectively, when used at a concentration of 5 μM, similar to arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607). Oleic acid (60 μM) induces release of intracellular calcium in human platelets. In vivo, oleic acid increases TNF-α, IL-8, IL-6, and IL-1β production, neutrophil accumulation, and apoptotic and necrotic cell death in mouse lung and has been used to induce lung injury in a mouse model of acute respiratory distress syndrome (ARDS).

Labelled Oleic acid. Obtained by the hydrolysis of various animal and vegetable fats and oils.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
WGK Germany  3

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