M8188347
Israpafant , 98% , 117279-73-9
CAS NO.：117279-73-9
Empirical Formula: C28H29ClN4S
Molecular Weight: 489.07
MDL number: MFCD00873428
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB7680.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 129.5-131.5° |
Description and Uses
Israpafant (Y-24180) is a potent, selective and long-acting platelet activation factor (PAF) receptor antagonist with IC50s of 0.84 nM and 3.84 nM against PAF-induced human and rabbit platelet aggregation, respectively. Israpafant stimulates both extracellular Ca2+ influx and intracellular Ca2+ release in prostate cancer cells. Israpafant suppresses the allergic cutaneous reactions including eosinophilia, cytokine production, edema and erythema in mice[1][2].
