S8999514
GW405833 hydrochloride , ≥98%(HPLC),solid , 180002-83-9
Synonym(s):
1-(2,3-Dichlorobenzoyl)-5-methoxy-2-methyl-(3-(morpholin-4-yl)ethyl)-1H-indole hydrochloride;L768;ML-SI1 hydrochloride
CAS NO.：180002-83-9
Empirical Formula: C23H24Cl2N2O3
Molecular Weight: 447.35
MDL number: MFCD08061200
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1070.68 | In Stock |
|
| 25mg | RMB4812.01 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 47-49℃ |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO at 10-15mg/ml. Also soluble in ethanol at ~5mg/ml. |
| form | solid |
| color | tan |
Description and Uses
It is a potent and selective CB2 receptor partial agonist (EC50 = 0.65 nM; maximum inhibition = 44.6%). Binds with high affinity to both human and rat CB2 receptors and displays ~ 1200-fold selectivity over CB1 (Ki values are 3.92 and 4772 nM for human recombinant CB2 and CB1 receptors respectively). Produces potent antihyperalgesic effects in several rodent models of pain.
