3-Acetamidophenylboronic acid , 98% , 78887-39-5

Synonym(s):
3-Acetamidobenzeneboronic acid

CAS NO.：78887-39-5

Empirical Formula: C8H10BNO3

Molecular Weight: 178.98

MDL number: MFCD00236013

PRODUCT Properties

• Melting point: 135 °C (lit.)
• Density: 1.23±0.1 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: soluble in Methanol
• pka: 8.04±0.10(Predicted)
• form: powder
• color: Light orange to Yellow to Green
• BRN: 3278316
• CAS DataBase Reference: 78887-39-5(CAS DataBase Reference)
• EPA Substance Registry System: Boronic acid, B-[3-(acetylamino)phenyl]- (78887-39-5)

Description and Uses

Reactant involved in:

• Suzuki-Miyaura coupling reactions
• Trifluoromethylation

Reactant involved in the synthesis of a variety of inhibitors including:

• NR2B subtype of NMDA receptor antagonists for antidepressant activity
• Biphenylylmethylimidazole derivatives for use as 17,20-lyase inhibitors
• (Indolyl)-3,5-substituted benzene analogs with antimitotic and antitumor activity
• Substituted pyrrolidines and tetrahydrofurans as AMPA receptor positive modulators

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36-26-37
• WGK Germany: 3
• F: 3-10
• HazardClass: IRRITANT
• HS Code: 29310095