(±)-3-Amino-1,2-propanediol , 97% , 616-30-8

Synonym(s):
1-Amino-2,3-propanediol;3-Amino-1,2-propanediol

CAS NO.：616-30-8

Empirical Formula: C3H9NO2

Molecular Weight: 91.11

MDL number: MFCD00008140

EINECS: 210-475-8

PRODUCT Properties

• Melting point: 55-57 °C
• Boiling point: 264-265 °C739 mm Hg(lit.)
• Density: 1.175 g/mL at 25 °C(lit.)
• vapor pressure: <1 hPa (20 °C)
• refractive index: n20/D 1.492(lit.)
• Flash point: >230 °F
• storage temp.: Store below +30°C.
• solubility: >1000g/l soluble
• pka: 12.11±0.35(Predicted)
• form: liquid (highly viscous)
• color: Clear colorless to pale yellow
• Specific Gravity: 1.175
• PH: 11 (100g/l, H2O, 20℃)
• Water Solubility: soluble
• Sensitive: Hygroscopic
• BRN: 1719121
• InChIKey: KQIGMPWTAHJUMN-UHFFFAOYSA-N
• LogP: -2.079 (est)
• CAS DataBase Reference: 616-30-8(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-1,2-propanediol(616-30-8)
• EPA Substance Registry System: 1,2-Propanediol, 3-amino- (616-30-8)

Description and Uses

3-Amino-1,2-propanediol (APD) is a calcium metabolism regulator useful in the treatment of Paget's disease, tumor-induced hypercalcemia and other bone disorders involving increased osteoclastic activity.

3-Amino-1,2-propanediol is used in the preparation of iohexol, which is a X-CT non-ionic contrast medium. It acts as a starting material in the production of specialty materials.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
• Hazard Codes: C,Xi
• Risk Statements: 34-36/37/38
• Safety Statements: 26-36/37/39-45-36
• RIDADR: UN 2735 8/PG 2
• WGK Germany: 2
• RTECS: TY2800000
• F: 10-21
• Hazard Note: Corrosive
• TSCA: Yes
• HazardClass: 8
• PackingGroup: III
• HS Code: 29221980
• Toxicity: LD50 orally in Rabbit: 7500 mg/kg
• Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)