Propranololhydrochloride , ≥99% , 318-98-9

Synonym(s):
(±)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride;(±)-Propranolol hydrochloride;DL-Propranolol hydrochloride

CAS NO.：318-98-9

Empirical Formula: C16H22ClNO2

Molecular Weight: 295.8

MDL number: MFCD00012558

EINECS: 206-268-7

PRODUCT Properties

• Melting point: 163-165 °C(lit.)
• Flash point: 9℃
• storage temp.: 2-8°C
• solubility: H₂O: 50 mg/mL, clear, colorless
• form: powder
• color: white
• Water Solubility: SOLUBLE
• Merck: 14,7840
• BRN: 4164259
• BCS Class: 1
• InChI: InChI=1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H
• InChIKey: ZMRUPTIKESYGQW-UHFFFAOYSA-N
• SMILES: C12C=CC=CC=1C=CC=C2OCC(O)CNC(C)C.Cl
• CAS DataBase Reference: 318-98-9(CAS DataBase Reference)
• EPA Substance Registry System: Propranolol hydrochloride (318-98-9)

Description and Uses

Propranolol, a β-adrenergic blocker, is most commonly used to reduce blood pressure; treatment of over-active thyroid and some types of tremor; prevention of migraine headaches and some heart-rhythm problems; used to decrease the number of angina attacks (pain from an inadequate oxygen supply to the heart); used after a heart attack to prevent further damage to the heart.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P301+P312+P330
• Hazard Codes: Xn,Xi,T,F
• Risk Statements: 22-39/23/24/25-23/24/25-11
• Safety Statements: 22-45-36/37-16-7
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 3
• RTECS: UB7525000
• F: 10
• HazardClass: IRRITANT
• HS Code: 29221990
• Hazardous Substances Data: 318-98-9(Hazardous Substances Data)
• Toxicity: LD50 in mice (mg/kg): 565 orally; 22 i.v.; 107 i.p. (Martin, Linee)