7-Azaindole , ≥98.0% , 271-63-6

Synonym(s):
1H-Pyrrolo(2,3-b)pyridine

CAS NO.：271-63-6

Empirical Formula: C7H6N2

Molecular Weight: 118.14

MDL number: MFCD00005606

EINECS: 205-981-0

PRODUCT Properties

• Melting point: 105-107 °C (lit.)
• Boiling point: 270 °C (753.1004 mmHg)
• Density: 1.1151 (rough estimate)
• refractive index: 1.5500 (estimate)
• Flash point: 270°C
• storage temp.: Sealed in dry,Room Temperature
• solubility: Chloroform, Methanol
• pka: 7.69±0.20(Predicted)
• form: Powder
• color: White to off-white
• BRN: 109667
• InChIKey: MVXVYAKCVDQRLW-UHFFFAOYSA-N
• CAS DataBase Reference: 271-63-6(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine(271-63-6)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine (271-63-6)

Description and Uses

7-Azaindole is the starting material for the synthesis of azaserotonin. Its derivatives are of great value in drug development, for example, as the backbone of protein kinase B (PKB/Akt) inhibitors. 7-Azaindole and its derivatives have a variety of biological activities, for example, 7-azatryptophan is able to inhibit the growth of tobacco and carrot cells. In addition, it also binds to the Erm enzyme (methyltransferase family), thereby conferring antibiotic resistance.

7-Azaindole is imidazolinone derivatives as CGRP receptor antagonists used in the treatment.
A heterocyclic molecule that can be utilized as a pharmaceutical building block.
Starting material in a recent synthesis of azaserotonin.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
• Hazard Codes: Xi,Xn
• Risk Statements: 36-41-37/38-22
• Safety Statements: 39-26-36/37/39
• WGK Germany: 3
• RTECS: UY8710000
• HazardClass: IRRITANT
• HS Code: 29339990