Acarbose Hydrate , ≥98% , 56180-94-0

Synonym(s):
4",6"-Dideoxy-4"-([1S]-[1,4,6/5]-4,5,6-trihydroxy-3-hydroxymethyl-2-yclohexenylamino)-maltotriose;Acarbose

CAS NO.：56180-94-0

Empirical Formula: C25H43NO18

Molecular Weight: 645.61

MDL number: MFCD00869592

EINECS: 260-030-7

PRODUCT Properties

• Melting point: 165-170°C
• alpha: D18 +165° (c = 0.4 in water)
• Boiling point: 675.05°C (rough estimate)
• Density: 1.4278 (rough estimate)
• refractive index: 1.6000 (estimate)
• storage temp.: 2-8°C
• solubility: Very soluble in water, soluble in methanol, practically insoluble in methylene chloride.
• form: Solid
• pka: 12.39±0.20(Predicted)
• color: White to Off-White
• biological source: bacterial (Actinoplanes)
• Water Solubility: Soluble in water.
• Merck: 14,18
• Stability: Hygroscopic
• InChIKey: XUFXOAAUWZOOIT-JMPDRRIHSA-N
• SMILES: C[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@@H]2CO)O[C@H]3[C@H](O)[C@@H](O)[C@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]1N[C@H]4C=C(CO)[C@@H](O)[C@H](O)[C@H]4O
• LogP: -7.935 (est)
• CAS DataBase Reference: 56180-94-0

Description and Uses

Acarbose, a complex oligosaccharide isolated from Actinoplanes, is reportedly useful as an adjuvant therapy in diabetes. By inhibiting alpha-glucosidase, acarbose delays carbohydrate metabolism in the gastrointestinal tract and modulates changes in food induced blood sugar levels.

antipsychotic: 5HT antagonist, dopamine antagonist, H1-antihistamine, alpha adrenergic blocker

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• PPE: Eyeshields, Gloves, type N95 (US)
• Safety Statements: 24/25
• WGK Germany: 1
• RTECS: LZ7153000
• HS Code: 29400090
• Storage Class: 11 - Combustible Solids
• Hazardous Substances Data: 56180-94-0(Hazardous Substances Data)
• Toxicity: LD50 orl-rat: 24 g/kg NIIRDN -,2,1995