2',3',5'-Tri-O-acetyl-2-amino-6-chloropurine Riboside , ≥97.0%(HPLC) , 16321-99-6

CAS NO.：16321-99-6

Empirical Formula: C16H18ClN5O7

Molecular Weight: 427.8

MDL number: MFCD03425473

PRODUCT Properties

• Melting point: 146.0 to 150.0 °C
• Boiling point: 637.0±65.0 °C(Predicted)
• Density: 1.70±0.1 g/cm3(Predicted)
• storage temp.: Refrigerator
• solubility: DMSO, Methanol
• form: Solid
• pka: 1.69±0.10(Predicted)
• color: Pale Green
• InChIKey: HLVGVJFVAKPFOZ-GNVCDDJRNA-N
• SMILES: [C@H]1(O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H]1OC(=O)C)N1C=NC2C(Cl)=NC(N)=NC1=2 |&1:0,2,8,13,r|

Description and Uses

2′,3′,5′-Tri-O-acetyl-6-chloroguanosine diacetate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P261-P280-P305+P351+P338-P304+P340
• HS Code: 2933599590