2-Amino-<i>N</i>-(2-chloro-6-methylphenyl)thiazole-5-carboxamide , >98.0% , 302964-24-5

CAS NO.：302964-24-5

Empirical Formula: C11H10ClN3OS

Molecular Weight: 267.73

MDL number: MFCD10000630

EINECS: 1806241-263-5

PRODUCT Properties

• Melting point: 208.0 to 212.0 °C
• Boiling point: 362.0±37.0 °C(Predicted)
• Density: 1.474±0.06 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• solubility: DMSO (Slightly), Methanol (Sparingly)
• form: powder to crystal
• pka: 11.09±0.70(Predicted)
• color: White to Light yellow
• InChI: InChI=1S/C11H10ClN3OS/c1-6-3-2-4-7(12)9(6)15-10(16)8-5-14-11(13)17-8/h2-5H,1H3,(H2,13,14)(H,15,16)
• InChIKey: VVOXTERFTAJMAA-UHFFFAOYSA-N
• SMILES: S1C(C(NC2=C(C)C=CC=C2Cl)=O)=CN=C1N
• CAS DataBase Reference: 302964-24-5(CAS DataBase Reference)

Description and Uses

2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide is a chemical compound characterized by its thiazole ring. This compound features an amino group (-NH2) and a carboxamide group (-C(=O)NH2), contributing to its potential as a bioactive molecule, making it of interest in medicinal chemistry and drug development.

2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide, is a precursor in the synthesis of Dasatinib (D193600), a protein tyrosine kinase inhibitor, and also for 2-Amino-thiazole-5-carboxylic Acid Phenylamide Derivatives, used as potent and selective anti-tumor drugs.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264-P270-P301+P312-P330-P501
• HS Code: 29333990