Acetohydrazide , >98.0% , 1068-57-1

Synonym(s):
Acetic acid hydrazide;Acetylhydrazine

CAS NO.：1068-57-1

Empirical Formula: C2H6N2O

Molecular Weight: 74.08

MDL number: MFCD00007610

EINECS: 213-948-7

PRODUCT Properties

• Melting point: 58-68 °C (lit.)
• Boiling point: 129 °C/18 mmHg (lit.)
• Density: 1.0968 (rough estimate)
• refractive index: 1.4264 (estimate)
• Flash point: >230 °F
• storage temp.: Keep in dark place,Inert atmosphere,2-8°C
• solubility: DMSO (Slightly), Methanol (Slightly)
• pka: 13.46±0.18(Predicted)
• form: Moist Crystals and Chunks
• color: White
• Water Solubility: soluble
• Sensitive: Hygroscopic
• BRN: 506165
• InChIKey: OFLXLNCGODUUOT-UHFFFAOYSA-N
• CAS DataBase Reference: 1068-57-1(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, hydrazide(1068-57-1)
• EPA Substance Registry System: Acetic acid hydrazide (1068-57-1)

Description and Uses

Acetic hydrazide is used as an antibiotic for the treatment of mycobacterium tuberculosis. It is also involved in the preparation of sunitinib b reacting with 5-fluoroisatin. Further, it inhibits mycolic acid biosynthesis. It serves as an important intermediate in organic synthesis such as nitric furosemide Long (nifuratrone) in medicine.
Acethydrazide can be used in the synthesis of (E)-N′-(2-hydroxybenzylidene)acetohydrazide, an ONO pincer ligand.

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H301-H315-H319-H341-H351
• Precautionary statements: P201-P301+P310+P330-P302+P352-P305+P351+P338
• Hazard Codes: Xn,T
• Risk Statements: 22-36/38-68-40-25
• Safety Statements: 26-36-45-36/37
• RIDADR: 1759
• WGK Germany: 1
• RTECS: AI1225000
• F: 3-8-10
• TSCA: Y
• HazardClass: 6.1
• PackingGroup: II
• HS Code: 29280090
• Toxicity: LD50 oral in bird - wild: 42200ug/kg
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)