2-<WBR>Aminomethyl-<WBR>1,4-<WBR>benzodioxane , 97% , 4442-59-5

Synonym(s):
(2,3-Dihydrobenzo-1,4-dioxin-2-yl)methylamine;1,4-Benzodioxane-2-methylamine;2,3-Dihydro-1,4-benzodioxin-2-methanamine

CAS NO.：4442-59-5

Empirical Formula: C9H11NO2

Molecular Weight: 165.19

MDL number: MFCD00203985

EINECS: 224-671-6

PRODUCT Properties

• Melting point: 184-188 °C
• Boiling point: 105-110 °C/3 mmHg
• Density: 1.1679 g/mL at 25 °C
• refractive index: n20/D 1.5594
• storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• solubility: Chloroform, Ethyl Acetate
• pka: 8.88±0.29(Predicted)
• form: Oil
• color: Clear Colorless
• CAS DataBase Reference: 4442-59-5(CAS DataBase Reference)

Description and Uses

2-Aminomethyl-1,4-benzodioxane is used in the synthesis of N-substituted (dihydrobenzodioxinyl)methylamine derivatives as D2 antagonists/5-HT1A partial agonists with potential as atypical antipsychotic agents in relation to affinity for α1 adrenoceptors.

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H315-H318-H335
• Precautionary statements: P280-P302+P352-P305+P351+P338+P310
• Hazard Codes: Xi
• Risk Statements: 34-41-37/38
• Safety Statements: 26-36/37/39
• RIDADR: 2735
• WGK Germany: 3
• RTECS: DF3676000
• HazardClass: IRRITANT
• HS Code: 2932990090
• Toxicity: LDLo intravenous in rabbit: 60mg/kg
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)