1-Bis(4-fluorophenyl)methyl piperazine , 97% , 27469-60-9

Synonym(s):
1-(4,4′-Difluorobenzhydryl)piperazine

CAS NO.：27469-60-9

Empirical Formula: C17H18F2N2

Molecular Weight: 288.33

MDL number: MFCD00038660

EINECS: 248-476-0

PRODUCT Properties

• Melting point: 88-92 °C(lit.)
• Boiling point: 130 °C
• Density: 1.1462 (estimate)
• vapor pressure: 0.001-0.003Pa at 20-25℃
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: soluble in Methanol,Toluene
• pka: 9.00±0.10(Predicted)
• form: Crystalline Powder
• color: White to yellow
• Water Solubility: 0.34 g/L (20 ºC)
• BRN: 620754
• Stability: Hygroscopic
• InChI: InChI=1S/C17H18F2N2/c18-15-5-1-13(2-6-15)17(21-11-9-20-10-12-21)14-3-7-16(19)8-4-14/h1-8,17,20H,9-12H2
• InChIKey: TTXIFFYPVGWLSE-UHFFFAOYSA-N
• SMILES: N1(C(C2=CC=C(F)C=C2)C2=CC=C(F)C=C2)CCNCC1
• LogP: 3.3-3.5 at pH7-11
• CAS DataBase Reference: 27469-60-9(CAS DataBase Reference)

Description and Uses

1-Bis(4-fluorophenyl)methyl piperazine may be used to synthesize 1-[bis(4-fluorophenyl)methyl]-4-[3-[(N-ethoxycarbonyl-N-phenyl)amino]-2-hydroxypropyl]piperazine and (R, S) 3-[4-(bis(4-fluorophenyl)methyl)piperazin-1-yl]dihydrofuran-2(3H)-one.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301-H315-H319-H335
• Precautionary statements: P301+P310+P330-P302+P352-P305+P351+P338
• Hazard Codes: T
• Risk Statements: 25-36/37/38
• Safety Statements: 26-45-36/37/39
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• F: 10-34
• Hazard Note: Toxic
• HazardClass: IRRITANT
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29335990
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)