A1244612
tert-Butyl Bromoacetate , 98% , 5292-43-3
CAS NO.：5292-43-3
Empirical Formula: C6H11BrO2
Molecular Weight: 195.05
MDL number: MFCD00000188
EINECS: 226-133-6
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 44-47 °C |
| Boiling point: | 50 °C10 mm Hg(lit.) |
| Density | 1.338 |
| vapor pressure | 1.62hPa at 25℃ |
| refractive index | n |
| Flash point: | 121 °F |
| storage temp. | 0-6°C |
| solubility | Chloroform, Ethyl Acetate (Slightly) |
| form | Liquid |
| Specific Gravity | 1.333 (20/4℃) |
| color | Clear colorless to yellow |
| Water Solubility | Miscible with ethanol, chloroform and ethyl acetate. Immiscible with water. |
| Sensitive | Lachrymatory |
| BRN | 1753010 |
| InChI | 1S/C6H11BrO2/c1-6(2,3)9-5(8)4-7/h4H2,1-3H3 |
| InChIKey | BNWCETAHAJSBFG-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)CBr |
| CAS DataBase Reference | 5292-43-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetic acid, bromo-, 1,1-dimethylethyl ester(5292-43-3) |
| EPA Substance Registry System | Acetic acid, bromo-, 1,1-dimethylethyl ester (5292-43-3) |
Description and Uses
tert-Butyl bromoacetate is used as an intermediate in the production of dyes, pharmaceuticals, agrochemicals and in organic compounds. It finds application as an alkylating agent. It plays an important role to prepare (2-oxo-4-vinyl-azetidin-1-yl)-acetic acid tert-butyl ester and in collagenase inhibitors synthesis.
Safety
| Symbol(GHS) |    GHS02,GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H226-H302-H314 |
| Precautionary statements | P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338 |
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi,F |
| Risk Statements | 10-36/37/38 |
| Safety Statements | 26-24/25-16 |
| RIDADR | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| F | 19 |
| Hazard Note | Irritant/Flammable/Lachrymatory |
| TSCA | TSCA listed |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 29159080 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Flam. Liq. 3 Skin Corr. 1B |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
