tert-Butyl Diethylphosphonoacetate , 95% , 27784-76-5

Synonym(s):
(Diethoxyphosphinyl)acetic acid 1,1-dimethylethyl ester;tert-Butyl (diethoxyphosphinyl)acetate;Diethyl tert-butoxycarbonylmethanephosphonate

CAS NO.：27784-76-5

Empirical Formula: C10H21O5P

Molecular Weight: 252.24

MDL number: MFCD00075414

EINECS: 000-000-0

PRODUCT Properties

• Boiling point: 100-103 °C/1.5 mmHg (lit.)
• Density: 1.074 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.431(lit.)
• Flash point: >230 °F
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• form: Liquid
• Specific Gravity: 1.074
• color: Clear colorless
• Water Solubility: Not miscible or difficult to mix in water.
• BRN: 2050126
• InChI: InChI=1S/C10H21O5P/c1-6-13-16(12,14-7-2)8-9(11)15-10(3,4)5/h6-8H2,1-5H3
• InChIKey: NFEGNISFSSLEGU-UHFFFAOYSA-N
• SMILES: C(OC(C)(C)C)(=O)CP(OCC)(OCC)=O
• CAS DataBase Reference: 27784-76-5(CAS DataBase Reference)

Description and Uses

tert-Butyl diethylphosphonoacetate is used as a reactant for preparation of hydroxymethylated dihydroxyvitamin D3 analogs via Wittig-Horner approach, as potential antitumor agents, synthesis of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat 3) and bicyclic triaminophosphine-promoted stereoselective synthesis of a,?-unsaturated esters, fluorides, and nitriles from aldehydes and ketones using Wadsworth-Emmons phosphonates

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280a-P305+P351+P338-P321-P332+P313-P337+P313
• Risk Statements: 36/38
• Safety Statements: 26-36-24/25
• WGK Germany: 3
• HS Code: 29319090