A1251412
4-Bromoanisole , 99% , 104-92-7
Synonym(s):
1-Bromo-4-methoxybenzene
CAS NO.：104-92-7
Empirical Formula: C7H7BrO
Molecular Weight: 187.03
MDL number: MFCD00000097
EINECS: 203-252-1
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 9-10 °C (lit.) |
| Boiling point: | 223 °C (lit.) |
| Density | 1.494 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 202 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Water Solubility | immiscible |
| Merck | 14,1428 |
| BRN | 1237590 |
| Dielectric constant | 7.4000000000000004 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChI | 1S/C7H7BrO/c1-9-7-4-2-6(8)3-5-7/h2-5H,1H3 |
| InChIKey | QJPJQTDYNZXKQF-UHFFFAOYSA-N |
| SMILES | COc1ccc(Br)cc1 |
| CAS DataBase Reference | 104-92-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1-bromo-4-methoxy-(104-92-7) |
| EPA Substance Registry System | Benzene, 1-bromo-4-methoxy- (104-92-7) |
Description and Uses
4-Bromoanisole finds application as an intermediate in synthetic chemistry. It is used in the preparation of aryl 1,3-diketones and ethyl 4-methoxycinnamate. It is a used as a brominating reagent. Further, it is used in Suzuki coupling reaction with phenylboronic acid as well as in Heck reaction.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315 |
| Precautionary statements | P264-P270-P280-P301+P312-P302+P352-P332+P313 |
| PPE | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
| Hazard Codes | Xn |
| Safety Statements | 23-24/25 |
| WGK Germany | 2 |
| RTECS | BZ8501000 |
| F | 8 |
| TSCA | TSCA listed |
| HS Code | 29093038 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Acute Tox. 4 Oral Skin Irrit. 2 |
| Toxicity | LD50 orl-mus: 2200 mg/kg GISAAA 44(12),19,79 |
