Benzenesulfonamide , 98% , 98-10-2

Synonym(s):
Benzenesulfonamide

CAS NO.：98-10-2

Empirical Formula: C6H7NO2S

Molecular Weight: 157.19

MDL number: MFCD00007930

EINECS: 202-637-1

PRODUCT Properties

• Melting point: 149-152 °C (lit.)
• Boiling point: 315.5±25.0 °C(Predicted)
• Density: 1.274 (estimate)
• bulk density: 700kg/m3
• refractive index: 1.5500 (estimate)
• Flash point: 250°C
• storage temp.: Store below +30°C.
• solubility: methanol: soluble25mg/mL
• pka: 10.1(at 25℃)
• form: Powder, Crystals and/or Chunks
• color: White to off-white
• Water Solubility: 4.3 g/L (16 ºC)
• BRN: 1100566
• InChI: 1S/C6H7NO2S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H2,7,8,9)
• InChIKey: KHBQMWCZKVMBLN-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)c1ccccc1
• CAS DataBase Reference: 98-10-2(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide(98-10-2)
• EPA Substance Registry System: Benzenesulfonamide (98-10-2)

Description and Uses

Biospecific adsorption of carbonic anhydrase to self-assembled monolayers of alkanethiolates that present benzenesulfonamide groups on gold. Biospecific binding of carbonic anhydrase to mixed sams presenting benzenesulfonamide ligands led to a model system for studying lateral steric effects. Benzenesulfonamide modifications at c-7 of ciprofloxacin change its primary target instreptococcus pneumoniae from topoisomerase iv to gyrase. Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264-P270-P301+P312-P501
• Hazard Codes: Xn
• Risk Statements: 22
• Safety Statements: 36
• WGK Germany: 3
• RTECS: DA9380000
• TSCA: TSCA listed
• HS Code: 29350090
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral
• Toxicity: LD50 orally in Rabbit: 991 mg/kg