Bestatin hydrochloride , ≥98%(HPLC) , 65391-42-6

Synonym(s):
N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine hydrochloride

CAS NO.：65391-42-6

Empirical Formula: C16H25ClN2O4

Molecular Weight: 344.83

MDL number: MFCD00058004

PRODUCT Properties

• Melting point: 216-218 °C
• storage temp.: 2-8°C
• solubility: H₂O: 25 mg/mL, clear, colorless
• form: White to off-white powder.
• color: White
• biological source: synthetic (organic)
• Water Solubility: Soluble in water (4 mg/ml, warm), DMSO (>25 mg/ml), methanol, acetic acid, dimethyl formamide, and 100% ethanol.
• BRN: 4628066
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO, distilled water, or ethanol may be stored at -20° for up to 1 month.
• InChI: 1S/C16H24N2O4.ClH/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11;/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22);1H/t12-,13+,14+;/m1./s1
• InChIKey: XGDFITZJGKUSDK-UDYGKFQRSA-N
• SMILES: O=C(N[C@@H](CC(C)C)C(O)=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1.Cl[H]
• CAS DataBase Reference: 65391-42-6(CAS DataBase Reference)

Description and Uses

Bestatin HCl (65391-42-6) inhibits leucine aminopeptidase and aminopeptidases B and N. Inhibits leukotriene A4 hydrolase. Displays immunostimulant activity via activation of macrophages and T lymphocytes. Displays antitumor activity.

competitive aminopeptidase B inhibitor

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P280-P305+P351+P338
• PPE: Eyeshields, Gloves, type N95 (US)
• Hazard Codes: Xn
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• F: 3-10
• HS Code: 29242995
• Storage Class: 11 - Combustible Solids