N-Benzylcinchoninium Chloride [Chiral Phase-Transfer Catalyst] , 99% , 69221-14-3

Synonym(s):
9-Hydroxy-1-(phenylmethyl)cinchonanium chloride;BCNC

CAS NO.：69221-14-3

Empirical Formula: C26H29ClN2O

Molecular Weight: 420.97

MDL number: MFCD00082423

EINECS: 273-915-8

PRODUCT Properties

• Melting point: 256 °C (dec.)(lit.)
• refractive index: 168.5 ° (C=0.4, MeOH:H2O=1:5)
• storage temp.: Inert atmosphere,Room Temperature
• solubility: slightly sol. in Methanol
• form: powder to crystaline
• color: White to Almost white
• optical activity: [α]20/D +169°, c = 0.4 in H2O
• BRN: 5232950
• InChIKey: FCHYSBWCOKEPNQ-YGNISETGSA-M
• SMILES: [Cl-].O[C@H]([C@H]1C[C@@H]2CC[N+]1(C[C@@H]2C=C)Cc3ccccc3)c4ccnc5ccccc45
• CAS DataBase Reference: 69221-14-3(CAS DataBase Reference)

Description and Uses

Phase-transfer catalyst involved in:

• Enantioselective alkylation of malonic diester with alkyl halides
• Hydrolysis of enol esters
• Asymmetric 6π electrocyclization for synthesis of functionalized indolines
• Asymmetric Michael addition
• Alkylation of monosubstituted indolinones with alkylhalides
• Asymmetric destruction and kinetic resolution of 1-benzylated Reissert compounds

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HS Code: 29339900
• Storage Class: 11 - Combustible Solids