4-Bromophenyl methyl sulfone , 98% , 3466-32-8

Synonym(s):
1-Bromo-4-(methylsulfonyl)benzene

CAS NO.：3466-32-8

Empirical Formula: C7H7BrO2S

Molecular Weight: 235.1

MDL number: MFCD00025065

EINECS: 222-421-0

PRODUCT Properties

• Melting point: 103-107 °C (lit.)
• Boiling point: 348.6±34.0 °C(Predicted)
• Density: 1.595±0.06 g/cm3(Predicted)
• storage temp.: Store at room temperature
• solubility: soluble in Methanol
• form: Crystals or Crystalline Powder
• color: White
• BRN: 2045675
• InChI: InChI=1S/C7H7BrO2S/c1-11(9,10)7-4-2-6(8)3-5-7/h2-5H,1H3
• InChIKey: FJLFSYRGFJDJMQ-UHFFFAOYSA-N
• SMILES: C1(Br)=CC=C(S(C)(=O)=O)C=C1
• CAS DataBase Reference: 3466-32-8(CAS DataBase Reference)

Description and Uses

4-Bromophenyl methyl sulfone may be used to synthesize:

• biaryl methyl sulfones
• 5-[[-4-(methylsulfonyl)phenyl]thio]thiophene-2-sulfonamide
• 1-[4-(methylsulfonyl)phenyl]-1H-pyrazole (Hmsppz)
• DuP 697 via reaction with (5-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)trimethylsilane

4-Bromophenyl methyl sulfone (1-bromo-4-(methylsulfonyl)benzene) can undergo coupling reaction with benzene sulfonamide in the presence of copper(I)iodide to form the corresponding N-aryl sulfonamide.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36/37/38
• Safety Statements: 22-24/25-36/37/39-26
• WGK Germany: 3
• Hazard Note: Irritant
• HS Code: 29309090