Bifonazole , ≥98%(HPLC) , 60628-96-8

Synonym(s):
1-(p,α-Diphenylbenzyl)imidazole;Bifonazole

CAS NO.：60628-96-8

Empirical Formula: C22H18N2

Molecular Weight: 310.4

MDL number: MFCD00865567

EINECS: 262-336-6

PRODUCT Properties

• Melting point: 142℃
• Boiling point: 440.55°C (rough estimate)
• Density: 1.1150 (rough estimate)
• refractive index: 1.7620 (estimate)
• storage temp.: Sealed in dry,Room Temperature
• solubility: Soluble in DMSO
• form: powder
• pka: 6.55±0.22(Predicted)
• color: white to off-white
• Merck: 14,1213
• InChI: InChI=1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H
• InChIKey: OCAPBUJLXMYKEJ-UHFFFAOYSA-N
• SMILES: C(C1C=CC=CC=1)(N1C=NC=C1)C1C=CC(C2C=CC=CC=2)=CC=1
• LogP: 4.770
• CAS DataBase Reference: 60628-96-8(CAS DataBase Reference)

Description and Uses

Bifonazole represents the first topical broad spectrum antimycotic approved for once daily administration. Its in vitro activity appears equivalent to its structural relative clotrimazole, being effective against dermatophytes, other filamentous fungi, dimorphic fungi and yeasts.

antibacterial

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P301+P312+P330
• Hazard Codes: Xn
• Risk Statements: 22
• WGK Germany: 1
• RTECS: NI3517000
• HS Code: 29332900
• Toxicity: LD50 in male mice, rats (mg/kg): 2629, 2854 orally (Schlüter)