4-Bromo-1-butyne , >97.0%(GC) , 38771-21-0

Synonym(s):
1-Bromo-3-butyne

CAS NO.：38771-21-0

Empirical Formula: C4H5Br

Molecular Weight: 132.99

MDL number: MFCD10000883

PRODUCT Properties

• Boiling point: 110 °C
• Density: 1.417 g/mL at 25 °C
• refractive index: 1.481
• Flash point: 24 °C
• storage temp.: Inert atmosphere,Store in freezer, under -20°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: clear liquid
• color: Colorless to Light yellow to Light orange
• Water Solubility: Immiscible with water.
• InChI: InChI=1S/C4H5Br/c1-2-3-4-5/h1H,3-4H2
• InChIKey: XLYOGWXIKVUXCL-UHFFFAOYSA-N
• SMILES: C#CCCBr

Description and Uses

4-Bromo-1-butyne is used as a reactant in the synthesis of:

• Macrocycles by cobalt-mediated [2+2+2] co-cyclotrimerization.
• 2,4,5-trisubstituted oxazoles by a gold-catalyzed formal [3+2] cycloaddition.
• Intramolecular 1,3-dipolar cycloaddition to synthesize 1,3,4-oxadiazoles.
• Lactones bearing alkynes for reductive cyclization in the preparation of azulene derivatives.
• Substituted α-pyrones by gold-catalyzed coupling reactions.

Safety

• Symbol(GHS): GHS02,GHS06
• Signal word: Danger
• Hazard statements: H226-H301-H317
• Precautionary statements: P210-P280-P301+P310+P330-P302+P352
• Hazard Codes: T
• Risk Statements: 10-25-43
• Safety Statements: 36/37-45
• RIDADR: UN 1992 6.1(3) / PGIII
• WGK Germany: 3
• HazardClass: 3
• PackingGroup: III
• HS Code: 29039990
• Limited Quantities: 5.0 L (1.3 gallons) (liquid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)