A1495712
3'-Bromo-4'-methylacetophenone , >98.0%(GC) , 40180-80-1
| Pack Size | Price | Stock | Quantity |
| 200MG | RMB48.00 | In Stock |
|
| 1G | RMB143.20 | In Stock |
|
| 5G | RMB293.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 42-46 °C(lit.) |
| Boiling point: | 118°C/3mmHg(lit.) |
| Density | 1.388±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Off-White to Pale Yellow |
| InChI | InChI=1S/C9H9BrO/c1-6-3-4-8(7(2)11)5-9(6)10/h3-5H,1-2H3 |
| InChIKey | PDJLFESXPVLVMR-UHFFFAOYSA-N |
| SMILES | C(=O)(C1=CC=C(C)C(Br)=C1)C |
Description and Uses
3''-Bromo-4''-methylacetophenone is used as a starting material in the synthesis of mansonone E which is used to make mansonone E dervivatives. These derivatives are potent inhibitors of topoisomerase II (Topo II) and topoisomerase I (Topo I) and are also potent antitumor agents. 3''-Bromo-4''-methylacetophenone is also used as a reagent in the synthesis of BAF312, Siponimod which has been tested in the treatment of patients suffering from relapsing-remitting multiple sclerosis.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
| HS Code | 2914390090 |
