2-Bromo-6-nitrophenol , >98.0% , 13073-25-1

CAS NO.：13073-25-1

Empirical Formula: C6H4BrNO3

Molecular Weight: 218

MDL number: MFCD02683216

EINECS: 629-309-4

PRODUCT Properties

• Melting point: 66-70 °C (lit.)
• Boiling point: 227.2±20.0 °C(Predicted)
• Density: 1.881±0.06 g/cm3(Predicted)
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Chloroform; Methanol
• pka: 5.36±0.24(Predicted)
• form: Solid
• color: Yellow
• InChI: InChI=1S/C6H4BrNO3/c7-4-2-1-3-5(6(4)9)8(10)11/h1-3,9H
• InChIKey: VEJSIOPQKQXJAT-UHFFFAOYSA-N
• SMILES: C1(O)=C([N+]([O-])=O)C=CC=C1Br
• CAS DataBase Reference: 13073-25-1(CAS DataBase Reference)
• EPA Substance Registry System: 2-Bromo-6-nitrophenol (13073-25-1)

Description and Uses

2-Bromo-6-nitrophenol is an intermediate used in the synthesis of N-Hydroxy Eltrombopag (H825795), which is a derivative compound of Eltrombopag (508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

Safety

• Symbol(GHS): GHS07,GHS06
• Signal word: Warning
• Hazard statements: H302-H315-H319-H301-H335
• Precautionary statements: P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501-P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36/37/38
• Safety Statements: 36/37-26
• WGK Germany: 3
• Hazard Note: Harmful
• HazardClass: IRRITANT
• HS Code: 29089990
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral