2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylicacid , 98+% , 376591-95-6

CAS NO.：376591-95-6

Empirical Formula: C13H9NO5

Molecular Weight: 259.21

MDL number: MFCD10001466

PRODUCT Properties

• Boiling point: 452.2±40.0 °C(Predicted)
• Density: 1.460±0.06 g/cm3(Predicted)
• storage temp.: Room Temperature
• solubility: Tetrahydrofuran; Methanol
• form: Solid
• pka: 3.96±0.10(Predicted)
• color: Yellow
• InChI: InChI=1S/C13H9NO5/c15-12-10(5-2-6-11(12)14(18)19)8-3-1-4-9(7-8)13(16)17/h1-7,15H,(H,16,17)
• InChIKey: JCFPSTQCDAZKJN-UHFFFAOYSA-N
• SMILES: C1(C2=CC=CC([N+]([O-])=O)=C2O)=CC=CC(C(O)=O)=C1

Description and Uses

3’-Nitro-2’-hydroxy[1,1’]-biphenyl-3-carboxylic Acid is an intermediate used in the synthesis of N-Hydroxy Eltrombopag (H825795), which is a derivative compound of Eltrombopag (508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313