(5-Carboxypentyl)triphenylphosphonium bromide , 98% , 50889-29-7

CAS NO.：50889-29-7

Empirical Formula: C24H26BrO2P

Molecular Weight: 457.34

MDL number: MFCD00055556

PRODUCT Properties

• Melting point: 197-201 °C
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Soluble in Chloroform and Methanol.
• form: Solid
• color: White to Off-White
• Sensitive: Hygroscopic
• InChI: InChI=1S/C24H25O2P.BrH/c25-24(26)19-11-4-12-20-27(21-13-5-1-6-14-21,22-15-7-2-8-16-22)23-17-9-3-10-18-23;/h1-3,5-10,13-18H,4,11-12,19-20H2;1H
• InChIKey: JUWYRPZTZSWLCY-UHFFFAOYSA-N
• SMILES: [P+](CCCCCC(=O)O)(C1C=CC=CC=1)(C1=CC=CC=C1)C1C=CC=CC=1.[Br-]
• CAS DataBase Reference: 50889-29-7(CAS DataBase Reference)

Description and Uses

(5-Carboxypentyl)(triphenyl)phosphonium bromide is used in medicine and as pharmaceutical intermediate. It is also employed as catalyst.
Reactant for:

1. Preparation of inhibitor of protein tyrosine phosphatase 1B for treatment of diabetes and obesity.
2. Synthesis of folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activity.
3. Preparation of peptide nucleic acids (PNA) with high specific activity.
4. Synthesis of roseophilin via Wittig/aldol methodology.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-36/37/39-22
• WGK Germany: 3
• HS Code: 2931599090