A2404512
(4-Carboxybutyl)triphenylphosphonium bromide , 98% , 17814-85-6
Synonym(s):
4-Carboxybutyltriphenylphosphonium bromide;5-(Triphenylphosphonio)pentanoic acid bromide;Carboxybutyltriphenylphosphonium bromide;NSC 147756
CAS NO.：17814-85-6
Empirical Formula: C23H24BrO2P
Molecular Weight: 443.31
MDL number: MFCD00011906
EINECS: 241-782-5
| Pack Size | Price | Stock | Quantity |
| 5G | RMB28.80 | In Stock |
|
| 25G | RMB102.40 | In Stock |
|
| 100G | RMB327.20 | In Stock |
|
| 500G | RMB1199.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 204-207 °C(lit.) |
| Boiling point: | 324.7-327.4℃ at 101.93-102.15kPa |
| bulk density | 360-400kg/m3 |
| Density | 1.371 at 20℃ |
| vapor pressure | 0Pa at 25℃ |
| Flash point: | 195°(383°F) |
| storage temp. | Store below +30°C. |
| solubility | DMSO, Methanol, Water |
| form | solid |
| color | White to Off-White |
| Water Solubility | Soluble in ethanol, methanol and soluble water. Insoluble in toluene and hexane. |
| Sensitive | Hygroscopic |
| BRN | 3586477 |
| InChI | 1S/C23H23O2P.BrH/c24-23(25)18-10-11-19-26(20-12-4-1-5-13-20,21-14-6-2-7-15-21)22-16-8-3-9-17-22;/h1-9,12-17H,10-11,18-19H2;1H |
| InChIKey | KQJPHSBFOSLICV-UHFFFAOYSA-N |
| SMILES | [Br-].OC(=O)CCCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3 |
| LogP | 0.146 |
| CAS DataBase Reference | 17814-85-6(CAS DataBase Reference) |
Description and Uses
- Used as a platform for delivery of pro-apoptotic peptides into the mitochondria of tumor cells
Reactant for preparation of:
- Ring skeletons via ring closing metathesis and double bond migration ring closing metathesis reactions
- Methyl alkenyl quinolones as antimycobacterial agents
- Prostaglandins and their drug analogs via Gold-catalyzed Meyer-Schuster rearrangement
- Diphenylmethylpiperazines as N-type calcium channel blockers as potential therapeutic agents
- Folate receptor-specific glycinamide ribonucleotide formyltransferase (GARFTase) inhibitors with antitumor activity
- Cycloalkylidene alkanols with antileishmanial activity, via Wittig reaction
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | 3278 |
| WGK Germany | 3 |
| HS Code | 29310095 |
| Storage Class | 6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Eye Dam. 1 |
