Methyltriphenylphosphonium bromide , 98% , 1779-49-3

Synonym(s):
Methyltriphenylphosphonium bromide

CAS NO.：1779-49-3

Empirical Formula: C19H18BrP

Molecular Weight: 357.22

MDL number: MFCD00011804

EINECS: 217-218-9

PRODUCT Properties

• Melting point: 230-234 °C (lit.)
• vapor pressure: 0.0000002 hPa
• Flash point: >240°C
• storage temp.: Inert atmosphere,Room Temperature
• solubility: H₂O: 0.1 g/mL, clear
• form: Powder
• color: White
• PH: 6.0-6.5 (400g/l, H2O, 20℃)
• Water Solubility: 400 g/L (25 ºC)
• Sensitive: Hygroscopic
• BRN: 3599467
• InChI: 1S/C19H18P.BrH/c1-20(17-11-5-2-6-12-17,18-13-7-3-8-14-18)19-15-9-4-10-16-19;/h2-16H,1H3;1H/q+1;/p-1
• InChIKey: LSEFCHWGJNHZNT-UHFFFAOYSA-M
• SMILES: [Br-].C[P+](c1ccccc1)(c2ccccc2)c3ccccc3
• LogP: -1.18
• CAS DataBase Reference: 1779-49-3(CAS DataBase Reference)
• NIST Chemistry Reference: Methyltriphenylphosphonium bromide(1779-49-3)
• EPA Substance Registry System: Phosphonium, methyltriphenyl-, bromide (1779-49-3)

Description and Uses

Methyltriphenylphosphonium bromide is used for methylenation through the Wittig reaction. It is utilized in the synthesis of an enyne and 9-isopropenyl -phenanthrene by using sodium amide as reagent. It is a lipophilic molecule and used to deliver molecules to specific cell components. Further, it acts as an antineoplastic agent.

Safety

• Symbol(GHS): GHS06,GHS09
• Signal word: Danger
• Hazard statements: H301-H411
• Precautionary statements: P273-P301+P310+P330
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xn,Xi
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 36/37-36-26
• RIDADR: UN 1390 4.3/PG 2
• WGK Germany: 3
• Autoignition Temperature: 410 °C
• TSCA: TSCA listed
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29310095
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3; toxic hazardous materials or hazardous materials causing chronic effects
• Hazard Classifications: Acute Tox. 3 Oral; Aquatic Chronic 2
• Toxicity: LD50 orally in Rabbit: 118 mg/kg