Caffeic acid phenethyl ester , 97% , 104594-70-9
Synonym(s):
Caffeic Acid Phenethyl Ester, Synthetic;CAPE;CAPE - CAS 104594-70-9 - Calbiochem
CAS NO.：104594-70-9
Empirical Formula: C17H16O4
Molecular Weight: 284.31
MDL number: MFCD00866470
EINECS: 627-151-0
| Pack Size | Price | Stock | Quantity |
| 25mg | RMB28.00 | In Stock |
|
| 250mg | RMB34.40 | In Stock |
|
| 1G | RMB48.00 | In Stock |
|
| 5G | RMB163.20 | In Stock |
|
| 25g | RMB396.00 | In Stock |
|
| 100g | RMB1078.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 127-129℃ |
| Boiling point: | 498.6±45.0 °C(Predicted) |
| Density | 1.266±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in ethyl acetate at 50mg/ml. Soluble in DMSO and ethanol. |
| pka | 8.46±0.20(Predicted) |
| form | White to off-white solid |
| color | off-white |
| biological source | synthetic |
| Sensitive | Light Sensitive |
| λmax | 323nm(lit.) |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
| Cosmetics Ingredients Functions | ANTIOXIDANT |
| InChI | 1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+ |
| InChIKey | SWUARLUWKZWEBQ-VQHVLOKHSA-N |
| SMILES | Oc1ccc(\C=C\C(=O)OCCc2ccccc2)cc1O |
| LogP | 3.734 (est) |
| CAS DataBase Reference | 104594-70-9(CAS DataBase Reference) |
Description and Uses
Phenylethyl caffeate is one of the allergens of propolis (bee glue); also contained in poplar-bud secretions.
Phenylethyl 3,4-dihydroxycinnamate is a potent and specific inhibitor of nuclear transcription factor, NF-κB, activation. It has been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation. It inhibits HIV-1 integrase and also inhibits proliferation of transformed cells. It induces apoptosis in transformed fibroblasts, and interferes with EGF signal transduction affecting both protein kinase C and ornithine decarboxylase activity.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-38-37-36 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | UD3334375 |
| HS Code | 29182900 |
| Storage Class | 11 - Combustible Solids |
