Cyclopropanecarboxylic acid , 98% , 1759-53-1

Synonym(s):
CPC-acid

CAS NO.：1759-53-1

Empirical Formula: C4H6O2

Molecular Weight: 86.09

MDL number: MFCD00001287

EINECS: 217-162-5

PRODUCT Properties

• Melting point: 14-17 °C (lit.)
• Boiling point: 182-184 °C (lit.)
• Density: 1.081 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.438(lit.)
• Flash point: 161 °F
• storage temp.: 2-8°C
• solubility: soluble in Chloroform, Ethyl Acetate
• form: Liquid
• pka: 4.83(at 25℃)
• color: Clear colorless to light yellow
• PH: 3 (10g/l, H2O, 22℃)
• BRN: 969839
• InChIKey: YMGUBTXCNDTFJI-UHFFFAOYSA-N
• LogP: 0.630
• CAS DataBase Reference: 1759-53-1(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid(1759-53-1)
• EPA Substance Registry System: Cyclopropanecarboxylic acid (1759-53-1)

Description and Uses

Cyclopropanecarboxylic Acid is used as a reagent in the synthesis of substituted 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors. Also used as a reagent in the synthesis of 2-alkyloxazoles as potent and selective PI4KIIIb inhibitors demonstrating inhibition of HCV replication.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
• Hazard Codes: C,Xi
• Risk Statements: 34-22
• Safety Statements: 26-36/37/39-45-27
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• RTECS: GZ1100000
• Hazard Note: Irritant/Corrosive
• TSCA: Yes
• HazardClass: 8
• PackingGroup: II
• HS Code: 29162000
• Toxicity: mouse,LD50,intraperitoneal,172mg/kg (172mg/kg),Journal of Pharmacy and Pharmacology. Vol. 21, Pg. 85, 1969.
• Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)