6-Carboxyfluorescein diacetate , 95% , 3348-03-6

CAS NO.：3348-03-6

Empirical Formula: C25H16O9

Molecular Weight: 460.39

MDL number: MFCD00036871

PRODUCT Properties

• Melting point: 152–153°C
• Boiling point: 701.6±60.0 °C(Predicted)
• Density: 1.57±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: DMSO: soluble
• pka: 6.4(at 25℃)
• form: Solid
• color: Light yellow or off-white solid
• PH Range: Weak green ' uorescence (6.0) to strong green ' uourescence (7.2)
• λmax: <300nm
• Major Application: Fluorescent probes, detecting cells, microorganisms, yeasts, antifungal agent, antibacterials agent
• Biological Applications: Analyzing/detecting cells;counting/ detecting/evaluating microorganisms;detecting/ measuring bacteria;quantifying adhesion of tumor cells to endothelial monolayers; measuring gas (carbon dioxide or ammonia) concentration in body luids; monitoring intracellular nitric oxide production;screening xenobiotic phloem mobility in plants; , studying low-density lipoprotein (LDL)/cholesterol metabolism;apoptosis assay;method for antifungal susceptibility testing; , as a substrate for measuring esterase activity
• InChI: 1S/C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25/h3-11H,1-2H3,(H,28,29)
• InChIKey: QMOGCCYGOPYYNT-UHFFFAOYSA-N
• SMILES: CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccc(cc45)C(O)=O)c1
• CAS DataBase Reference: 3348-03-6(CAS DataBase Reference)

Description and Uses

6-Carboxyfluorescein diacetate is a membrane-permeant prodrug of 6-Carboxyfluorescein, which has been used to differentiate viable cells from apoptotic cells.

6-Carboxyfluorescein Diacetate is a fluorescent polyanionic probe used to detect changes intracellular pH. In addition, 6-Carboxyfluorescein Diacetate derivatives can be used as staining agents for flow cytometry to visualize cells undergoing apoptosis or necrosis.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• PPE: Eyeshields, Gloves, type N95 (US)
• WGK Germany: 3
• F: 10-21
• HS Code: 29322090
• Storage Class: 11 - Combustible Solids