A2323012
o-Cresol , StandardforGC,≥99.7%(GC) , 95-48-7
Synonym(s):
o-Cresol;o-Cresol solution;2-Hydroxytoluene, 2-Methylphenol;2-Methylphenol;o-Cresol
CAS NO.：95-48-7
Empirical Formula: C7H8O
Molecular Weight: 108.14
MDL number: MFCD00002226
EINECS: 202-423-8
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 29-31 °C (lit.) |
| Boiling point: | 191 °C (lit.) |
| Density | 1.048 g/mL at 25 °C |
| vapor density | 3.72 (vs air) |
| vapor pressure | 0.3 mm Hg ( 20 °C) |
| FEMA | 3480 | O-CRESOL |
| refractive index | 1.5361 |
| Flash point: | 178 °F |
| storage temp. | under inert gas |
| solubility | 20g/l |
| form | Liquid or Low Melting Solid |
| pka | 10.2(at 25℃) |
| color | white to brown |
| Odor | at 0.01 % in dipropylene glycol. musty phenolic plastic medicinal herbal leathery |
| PH | 4.8 (20g/l, H2O, 20℃) |
| explosive limit | 1.47%, 148°F |
| Odor Threshold | 0.00028ppm |
| Odor Type | phenolic |
| biological source | synthetic |
| Water Solubility | 20 g/L (20 ºC) |
| Merck | 14,2579 |
| JECFA Number | 691 |
| BRN | 506917 |
| Henry's Law Constant | 0.34 at 5.25 °C, 0.61 at 10.00 °C, 1.57 at 20.00 °C, 2.33 at 25.00 °C (dynamic equilibrium system-
GC, Feigenbrugel et al., 2004a) |
| Exposure limits | NIOSH REL: TWA 2.3 ppm (10 mg/m3), IDLH 250 ppm; OSHA PEL: TWA 5
ppm (22 mg/m3); ACGIH TLV: TWA for all isomers 5 ppm (adopted). |
| Dielectric constant | 5.8（-5℃） |
| Stability: | Stable, but light and air sensitive. Combustible. Incompatible with oxidizing agents, bases. |
| Major Application | agriculture cleaning products cosmetics environmental flavors and fragrances food and beverages personal care |
| Cosmetics Ingredients Functions | ANTIMICROBIAL PERFUMING |
| Cosmetic Ingredient Review (CIR) | o-Cresol (95-48-7) |
| InChI | 1S/C7H8O/c1-6-4-2-3-5-7(6)8/h2-5,8H,1H3 |
| InChIKey | QWVGKYWNOKOFNN-UHFFFAOYSA-N |
| SMILES | Cc1ccccc1O |
| LogP | 1.95 at 20℃ |
| Surface tension | 35.86mN/m at 298.15K |
| CAS DataBase Reference | 95-48-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 2-methyl-(95-48-7) |
| EPA Substance Registry System | o-Cresol (95-48-7) |
Description and Uses
Disinfectant; phenolic resins; tricresyl phosphate; ore flotation; textile scouring agent; organic intermediate; manufacturing salicylaldehyde, coumarin, and herbicides; surfactant; synthetic food flavors (para isomer only); food antioxidant; dye, perfume, plastics, and resins manufacturing.
Safety
| Symbol(GHS) |    GHS05,GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H301+H311-H314-H411 |
| Precautionary statements | P260-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 |
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 24/25-34-39/23/24/25-23/24/25 |
| Safety Statements | 36/37/39-45-36/37 |
| RIDADR | UN 3455 6.1/PG 2 |
| OEB | B |
| OEL | TWA: 2.3 ppm (10 mg/m3) |
| WGK Germany | 1 |
| RTECS | GO6300000 |
| F | 8-23 |
| Autoignition Temperature | 555 °C |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 29071200 |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 3 Oral Aquatic Chronic 3 Eye Dam. 1 Skin Corr. 1B |
| Hazardous Substances Data | 95-48-7(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 1.35 g/kg (Deichmann, Witherup) |
| IDLA | 250 ppm |
