Coumarin 7 , 98% , 27425-55-4

Synonym(s):
3-(2-Benzimidazolyl)-7-(diethylamino)coumarin

CAS NO.：27425-55-4

Empirical Formula: C20H19N3O2

Molecular Weight: 333.38

MDL number: MFCD00051348

EINECS: 248-451-4

PRODUCT Properties

• Melting point: 234-237 °C(lit.)
• Boiling point: 470.35°C (rough estimate)
• Density: 1.2071 (rough estimate)
• refractive index: 1.6200 (estimate)
• storage temp.: -20°C
• solubility: DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: insol; PBS (pH 7.2): insol
• form: Powder
• pka: 10.83±0.10(Predicted)
• color: Bright yellow
• Appearance: White to Light yellow powder to crystal
• λmax: 438 nm
• InChI: InChI=1S/C20H19N3O2/c1-3-23(4-2)14-10-9-13-11-15(20(24)25-18(13)12-14)19-21-16-7-5-6-8-17(16)22-19/h5-12H,3-4H2,1-2H3,(H,21,22)
• InChIKey: GOLORTLGFDVFDW-UHFFFAOYSA-N
• SMILES: C1(=O)OC2=CC(N(CC)CC)=CC=C2C=C1C1NC2=CC=CC=C2N=1
• LogP: 3.68
• CAS DataBase Reference: 27425-55-4(CAS DataBase Reference)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 3-(1H-benzimidazol-2-yl)-7-(diethylamino)- (27425-55-4)

Description and Uses

Coumarin 7 is an extensively employed synthetic compound within the biomedical sector. It stands as an indispensable fluorescent probe instrumental in scrutinizing multifarious biological mechanisms encompassing the domains of pharmaceutical conveyance, enzymatic operations, and cellular visualization. Furthermore, its profound antioxidant and anti-inflammatory attributes have been recognized, thus unveiling promising therapeutic capabilities towards maladies like cancer and neurodegenerative ailments.

Coumarin is also known as benzoαpyrone. Coumarin 7 is a laser dye that is usually found in the nature. Dyes and metabolites.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-20/21/22
• Safety Statements: 26-38-37/39
• WGK Germany: 3
• HS Code: 29332900