4-Chloro-7-azaindole , 98% , 55052-28-3

Synonym(s):
4-Chloro-1H-pyrrolo[2,3-b]pyridine

CAS NO.：55052-28-3

Empirical Formula: C7H5ClN2

Molecular Weight: 152.58

MDL number: MFCD08272232

EINECS: 626-806-8

PRODUCT Properties

• Melting point: 176-181 °C
• Density: 1.425±0.06 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• pka: 12.98±0.40(Predicted)
• form: solid
• color: Light yellow to brown
• Water Solubility: Slightly soluble in water.
• InChI: InChI=1S/C7H5ClN2/c8-6-2-4-10-7-5(6)1-3-9-7/h1-4H,(H,9,10)
• InChIKey: HNTZVGMWXCFCTA-UHFFFAOYSA-N
• SMILES: C12NC=CC1=C(Cl)C=CN=2
• CAS DataBase Reference: 55052-28-3(CAS DataBase Reference)

Description and Uses

4-Chloro-7-azaindole belongs to the class of azaindole compounds, which has anticancer, antibacterial, antiviral and other biological activities. 4-Chloro-7-azaindole is mainly used as an organic intermediate in the preparation of 7-azaindole derivatives, GDC-0575, and Janus kinase inhibitors.

A useful intermediate for drug discovery research such as used in the synthesis of 7-azaindole derivatives, synthetic cytokinin analogues.

Safety

• Symbol(GHS): GHS05,GHS06
• Signal word: Danger
• Hazard statements: H301-H315-H318-H335
• Precautionary statements: P280-P301+P310+P330-P302+P352-P305+P351+P338+P310
• Hazard Codes: Xi,Xn
• Risk Statements: 22-37/38-41
• Safety Statements: 26-39
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• HazardClass: IRRITANT
• HazardClass: 6.1
• PackingGroup: Ⅲ
• HS Code: 29339900
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)