6-Chloropurine riboside , 99% , 5399-87-1

Synonym(s):
6-Chloropurine-9-β-D-ribofuranoside

CAS NO.：5399-87-1

Empirical Formula: C10H11ClN4O4

Molecular Weight: 286.67

MDL number: MFCD00005738

EINECS: 226-438-4

PRODUCT Properties

• Melting point: 158-162 °C (dec.) (lit.)
• Boiling point: 614.8±65.0 °C(Predicted)
• Density: 2.03±0.1 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: DMSO (Sparingly, Heated), Methanol (Slightly, Heated), Water (Slightly, Heated,
• pka: 13.06±0.70(Predicted)
• form: Powder
• color: White to slightly yellow
• Water Solubility: Soluble in water. (10.6 mg/mL)
• BRN: 40573
• InChI: InChI=1/C10H11ClN4O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2/t4-,6-,7-,10-/s3
• InChIKey: XHRJGHCQQPETRH-HMEJCUHCSA-N
• SMILES: OC[C@H]1O[C@@H](N2C3=C(C(Cl)=NC=N3)N=C2)[C@H](O)[C@@H]1O |&1:2,4,15,17,r|
• CAS DataBase Reference: 5399-87-1(CAS DataBase Reference)

Description and Uses

6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. 6-Chloropurine riboside, especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P271-P280
• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: UO7520800
• F: 10-23
• HS Code: 29349990