(R)-(+)-3-Chloro-1-phenyl-1-propanol , >98.0%(GC) , 100306-33-0

Synonym(s):
α-(2-Chloroethyl)benzyl alcohol;(R)-(+)-α-(2-Chloroethyl)benzyl alcohol;(R)-(+)-3-Chloro-1-phenylpropanol

CAS NO.：100306-33-0

Empirical Formula: C9 H11 Cl O

Molecular Weight: 170.64

MDL number: MFCD00075128

EINECS: 627-168-3

PRODUCT Properties

• Melting point: 58-60 °C (lit.)
• alpha: 26 º (c=1, chloroform)
• Boiling point: 296.4±20.0 °C(Predicted)
• Density: 1.149±0.06 g/cm3(Predicted)
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Powder
• pka: 13.92±0.20(Predicted)
• color: White to yellow
• optical activity: [α]24/D +26°, c = 1 in chloroform
• BRN: 5250766
• InChI: InChI=1/C9H11ClO/c10-7-6-9(11)8-4-2-1-3-5-8/h1-5,9,11H,6-7H2/t9-/s3
• InChIKey: JZFUHAGLMZWKTF-SECBINFHSA-N
• SMILES: [C@@H](C1C=CC=CC=1)(O)CCCl |&1:0,r|
• CAS DataBase Reference: 100306-33-0(CAS DataBase Reference)

Description and Uses

(R)-(+)-3-Chloro-1-phenyl-1-propanol may be used as a building block in the synthesis of antidepressants such as (R)- and (S)-tomoxetine, fluoxetine and nisoxetine. It may also be used in the synthesis of biologically active 2-substituted chromans such as tephrowatsin E.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 29062990