A2452612
2-Chloro-6-fluorobenzoic Acid , ≥98.0% , 434-75-3
CAS NO.：434-75-3
Empirical Formula: C7H4ClFO2
Molecular Weight: 174.56
MDL number: MFCD00002417
EINECS: 207-105-2
| Pack Size | Price | Stock | Quantity |
| 5G | RMB27.20 | In Stock |
|
| 25G | RMB65.60 | In Stock |
|
| 100G | RMB172.00 | In Stock |
|
| 500G | RMB592.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 155-157 °C(lit.) |
| Boiling point: | 263.7±20.0 °C(Predicted) |
| Density | 1.4016 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 2.04±0.10(Predicted) |
| form | powder to crystal |
| color | White to Gray to Brown |
| BRN | 973857 |
| InChI | InChI=1S/C7H4ClFO2/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H,10,11) |
| InChIKey | XNTIGDVFBDJLTQ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=C(F)C=CC=C1Cl |
| CAS DataBase Reference | 434-75-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Chloro-6-fluorobenzoic acid(434-75-3) |
Description and Uses
2-Chloro-6-fluorobenzoic Acid is a versatile reactant used in the synthesis of biaryls via decarboxylative Pd-catalyzed cross-coupling with aryl iodides. Also used in the preparation of fluorinated biaryls and heterobiaryls using copper catalyzed decarboxylative cross-coupling of aryl and heteroalyl iodides or bromides with potassium polyfluorobenzoates.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280a-P304+P340-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-37/38-36-20/21/22 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29163900 |
