6-Chlorooxindole , ≥98.0% , 56341-37-8

Synonym(s):
6-Chloro-1,3-dihydroindol-2-one;6-Chlorooxindole

CAS NO.：56341-37-8

Empirical Formula: C8H6ClNO

Molecular Weight: 167.59

MDL number: MFCD00209962

EINECS: 1312995-182-4

PRODUCT Properties

• Melting point: 195-199 °C (lit.)
• Boiling point: 329.0±42.0 °C(Predicted)
• Density: 1.362±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Room Temperature
• solubility: soluble in Dimethylformamide
• form: powder to crystal
• pka: 13.39±0.20(Predicted)
• color: Light yellow to Brown
• InChI: InChI=1S/C8H6ClNO/c9-6-2-1-5-3-8(11)10-7(5)4-6/h1-2,4H,3H2,(H,10,11)
• InChIKey: CENVPIZOTHULGJ-UHFFFAOYSA-N
• SMILES: N1C2=C(C=CC(Cl)=C2)CC1=O
• CAS DataBase Reference: 56341-37-8(CAS DataBase Reference)

Description and Uses

6-Chlorooxindole is an organic compound that has been used in the pharmaceutical industry as a hydrogen bond donor and a dihydrate salt. It is an aromatic heterocycle with two rings, one of which is an oxindole ring. 6-Chlorooxindole has been shown to be stable at low pH and high temperatures, with the exception of hydrochloric acid. It is also soluble in water and can be prepared in a variety of ways, including by reacting benzene with nitrous acid or by heating oxindole with sodium hydroxide. 6-Chlorooxindole can be found as a component in some pharmaceutical preparations such as carbamazepine and ziprasidone. It can also be found as a component of the drug chlorpromazine.

6-Chlorooxindole is a useful research chemical used in the design of potent non-peptide MDM2 inhibitors.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H317
• Precautionary statements: P280-P301+P312+P330-P302+P352
• Hazard Codes: Xn,Xi
• Risk Statements: 22-43-36/37/38
• Safety Statements: 37/39-36-26
• WGK Germany: 3
• Hazard Note: Irritant
• HS Code: 29337900