Ciprofloxacin , ≥98% , 85721-33-1

Synonym(s):
1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid;Ciprobay

CAS NO.：85721-33-1

Empirical Formula: C17H18FN3O3

Molecular Weight: 331.34

MDL number: MFCD00185755

EINECS: 617-751-0

PRODUCT Properties

• Melting point: 255-257°C
• Boiling point: 581.8±50.0 °C(Predicted)
• Density: 1.461±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Inert atmosphere,2-8°C
• solubility: Soluble in 0.1N HCl at 25mg/ml. Poorly soluble in DMSO
• pka: pKa 4.04 (Uncertain)
• form: powder
• color: White to Almost white
• Water Solubility: 86mg/L(25 ºC)
• Merck: 14,2314
• BRN: 3568352
• InChI: InChI=1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)
• InChIKey: MYSWGUAQZAJSOK-UHFFFAOYSA-N
• SMILES: N1(C2CC2)C2=C(C=C(F)C(N3CCNCC3)=C2)C(=O)C(C(O)=O)=C1
• CAS DataBase Reference: 85721-33-1(CAS DataBase Reference)
• EPA Substance Registry System: Ciprofloxacin (85721-33-1)

Description and Uses

Ciprofloxacin is a quinolone antibacterial related to recently marketed norfloxacin (10), ofloxacin (2), pefloxacin (2) and enoxacin. It has a broad spectrum of activity against gram-positive and gram-negative bacteria, and is useful in the treatment of urinary and upper respiratory tract infections.

Ciprofloxacin, inhibits bacterial DNA gyrase (topoisomerase). Inhibits cell division and causes double-strand breaks in the bacterial chromosome.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H412
• Precautionary statements: P273-P501
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36-24/25
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 2
• RTECS: VB1993800
• HS Code: 29339900
• Hazardous Substances Data: 85721-33-1(Hazardous Substances Data)