Carboxy-PTIO potassium salt , 98% , 148819-94-7
CAS NO.：148819-94-7
Empirical Formula: C14H16KN2O4*
Molecular Weight: 315.39
MDL number: MFCD00216153
| Pack Size | Price | Stock | Quantity |
| 10MG | RMB959.20 | In Stock |
|
| 50mg | RMB3199.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 141-143°C |
| storage temp. | 2-8°C |
| solubility | H2O: >20 mg/mL |
| form | solid |
| color | blue |
| biological source | synthetic (organic) |
| Water Solubility | Soluble in water. Also soluble in ethanol, methanol, DMSO or DMF. |
| Stability: | Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month. |
| InChI | 1S/C14H17N2O4.K/c1-13(2)14(3,4)16(20)11(15(13)19)9-5-7-10(8-6-9)12(17)18;/h5-8H,1-4H3,(H,17,18);/q;+1/p-1 |
| InChIKey | VYEUQMVIGXFZQU-UHFFFAOYSA-M |
| SMILES | [K+].CC1(C)N([O])C(c2ccc(cc2)C([O-])=O)=[N+]([O-])C1(C)C |
| CAS DataBase Reference | 148819-94-7(CAS DataBase Reference) |
Description and Uses
A nitric oxide (NO) scavenger. Carboxy-PTIO (148819-94-7) reacts with NO with 1:1 stoichiometry1 producing NO2–/NO3–. In LPS-induced endotoxin shock, carboxy-PTIO reversed hypotension and renal dysfunction and increased survival in a rat model.2 A very useful tool for probing the involvement of NO in physiological processes.3,4
Carboxy-PTIO potassium salt has been used to check the generation of hydroxyl radicals or nitric in reaction mixtures to examine the generation of nitric oxide in reaction mixture. It has also been added to neurons to analyse its effect on glucose/oxygen/serum deprivation (GOSD) condition(4)
Safety
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 2918999090 |
| Storage Class | 11 - Combustible Solids |
