4,6-Dichloropyrimidine , 98% , 1193-21-1

CAS NO.：1193-21-1

Empirical Formula: C4H2Cl2N2

Molecular Weight: 148.98

MDL number: MFCD00006109

EINECS: 214-770-2

PRODUCT Properties

• Melting point: 65-67 °C (lit.)
• Boiling point: 176 °C (lit.)
• Density: 1.6445 (rough estimate)
• vapor pressure: 30-390Pa at 20-50℃
• refractive index: 1.6300 (estimate)
• Flash point: 176°C
• storage temp.: Inert atmosphere,2-8°C
• solubility: 95% ethanol: soluble50mg/mL, clear to very slightly hazy, colorless to yellow
• pka: -4.20±0.17(Predicted)
• form: Crystals
• color: Yellow-green
• BRN: 111195
• InChIKey: XJPZKYIHCLDXST-UHFFFAOYSA-N
• LogP: 1.45 at 25℃ and pH7.2
• Surface tension: 65.72mN/m at 1g/L and 20℃
• CAS DataBase Reference: 1193-21-1(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrimidine, 4,6-dichloro-(1193-21-1)

Description and Uses

4,6-Dichloropyrimidine was used in the synthesis of N-substituted azacalix[4]pyrimidines. It was used as starting reagent for the synthesis of disubstituted pyrimidines by tandem amination and Suzuki-Miyaura cross-coupling. It was also used in a biarylpyrimidine synthesis involving biaryl cross-coupling.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
• Hazard Codes: C
• Risk Statements: 34-20/21/22-36/37
• Safety Statements: 26-36/37/39-45-27
• RIDADR: UN 3263 8/PG 2
• WGK Germany: 3
• F: 19
• Hazard Note: Corrosive
• HazardClass: 8
• PackingGroup: II
• HS Code: 29335990