2,4-Dichloro-5-methylpyrimidine , 98% , 1780-31-0

CAS NO.：1780-31-0

Empirical Formula: C5H4Cl2N2

Molecular Weight: 163

MDL number: MFCD00023197

EINECS: 217-227-8

PRODUCT Properties

• Melting point: 26-28 °C (lit.)
• Boiling point: 108-109 °C/11 mmHg (lit.)
• Density: 1.39 g/mL at 25 °C (lit.)
• refractive index: 1.6300 (estimate)
• Flash point: >230 °F
• storage temp.: Inert atmosphere,2-8°C
• solubility: Soluble in chloroform, ether, ethyl acetate and toluene
• pka: -2.44±0.29(Predicted)
• form: powder to lump to clear liquid
• color: White or Colorless to Almost white or Almost colorless
• Sensitive: Lachrymatory
• InChI: InChI=1S/C5H4Cl2N2/c1-3-2-8-5(7)9-4(3)6/h2H,1H3
• InChIKey: DQXNTSXKIUZJJS-UHFFFAOYSA-N
• SMILES: C1(Cl)=NC=C(C)C(Cl)=N1
• CAS DataBase Reference: 1780-31-0(CAS DataBase Reference)
• EPA Substance Registry System: Pyrimidine, 2,4-dichloro-5-methyl- (1780-31-0)

Description and Uses

2,4-Dichloro-5-methylpyrimidine, is used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine. It can react with piperidineto produce 2-chloro-5-methyl-4-piperidin-1-yl-pyrimidine. This reaction will need solvent dioxane.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
• Hazard Codes: C
• Risk Statements: 34
• Safety Statements: 26-36/37/39-45-27
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 8
• PackingGroup: III
• HS Code: 29335990
• Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)