D-ribo-Phytosphingosine , ≥98.0% , 554-62-1

Synonym(s):
D-Ribo-1,3,4-trihydroxy-2-aminooctadecane;D-Ribo-2-aminooctadecane-1,3,4-triol;4-Hydroxysphinganine;PHS

CAS NO.：554-62-1

Empirical Formula: C18H39NO3

Molecular Weight: 317.51

MDL number: MFCD02259274

EINECS: 205-516-1

PRODUCT Properties

• Melting point: 102 °C
• Boiling point: 483.7±40.0 °C(Predicted)
• Density: 0.983
• vapor pressure: 0.2Pa at 20℃
• refractive index: 9 ° (C=1, Pyridine)
• storage temp.: −20°C
• solubility: Soluble in Ethanol (up to 2 mg/ml).
• pka: 11.91±0.45(Predicted)
• form: White to off-white solid.
• color: White
• Water Solubility: 2.6mg/L at 20℃
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in ethanol may be stored at -20°C for up to 1 month.
• InChI: InChI=1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
• InChIKey: AERBNCYCJBRYDG-KSZLIROESA-N
• SMILES: C(O)[C@H](N)[C@H](O)[C@H](O)CCCCCCCCCCCCCC
• LogP: 6.2 at 22℃

Description and Uses

Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans. It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate. Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors. It is essential in the heat stress response in S. cerevisiae. [Matreya, LLC. Catalog No. 1330]

Phytosphingosine is a natural anti-microbial compound and it is involved in several cellular processes such as cell differentiation and anti-inflammation.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• WGK Germany: 1
• HS Code: 29221990