β-Sitosterol , >75.0% , 83-46-5

Synonym(s):
β-Sitosterol;beta-Sitosterol;22,23-Dihydrostigmasterol;24α-Ethylcholesterol;5-Stigmasten-3β-ol

CAS NO.：83-46-5

Empirical Formula: C29H50O

Molecular Weight: 414.72

MDL number: MFCD00003631

EINECS: 201-480-6

PRODUCT Properties

• Melting point: 136-140 °C(lit.)
• alpha: -28 º (c=2, CHCl3)
• Boiling point: 473.52°C (rough estimate)
• Density: 0.9540 (rough estimate)
• refractive index: 1.5000 (estimate)
• storage temp.: 2-8°C
• solubility: chloroform: 20 mg/mL, clear, colorless
• pka: 15.03±0.70(Predicted)
• form: White solid
• color: White to Off-White
• biological source: synthetic
• optical activity: -3725 (c 2, CHCl3)
• Water Solubility: INSOLUBLE
• Merck: 14,8556
• BRN: 1916165
• InChIKey: KZJWDPNRJALLNS-VJSFXXLFSA-N
• LogP: 10.482 (est)
• CAS DataBase Reference: 83-46-5(CAS DataBase Reference)
• NIST Chemistry Reference: «beta»-Sitosterol(83-46-5)
• EPA Substance Registry System: .beta.-Sitosterol (83-46-5)

Description and Uses

24α-ethyl Cholesterol is a naturally occurring plant sterol with antioxidant, anticancer, anti-inflammatory, angiogenic, chemopreventive, and immunomodulatory activities. It inhibits the absorption of dietary and endogenously-produced cholesterol from the small intestine, reducing blood cholesterol concentrations. Because of its nutraceutical benefits, 24α-ethyl cholesterol has been used as a food additive intended to lower LDL cholesterol. 24α-ethyl Cholesterol (0.1 - 100 μM) can dose-dependently induce adipogenesis and lipolysis in rat primary preadipocytes as well as stimulate glucose uptake in differentiated adipocytes.

A common sterol in plants. Isolated from wheat germ oil, corn oil. Antilipemic. Used in the treatment of prostatic adenoma.This compound is a contaminant of emerging concern (CECs)

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H302-H315-H319-H331-H336-H351-H361d-H372-H412
• Precautionary statements: P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
• Hazard Codes: Xn,Xi
• Risk Statements: 22-38-40-48/20/22-36/37/38-67-36/38-20-63
• Safety Statements: 22-24/25-36-26-36/37
• RIDADR: UN 1888 6.1/PG 3
• WGK Germany: 3
• RTECS: WJ2600000
• F: 10
• HS Code: 29061990