2′-Deoxyguanosine monohydrate , ≥99% , 312693-72-4
CAS NO.：312693-72-4
Empirical Formula: C10H13N5O4
Molecular Weight: 267.24
MDL number: MFCD00150760
EINECS: 628-392-4
| Pack Size | Price | Stock | Quantity |
| 25MG | RMB23.20 | In Stock |
|
| 100MG | RMB31.20 | In Stock |
|
| 1G | RMB60.00 | In Stock |
|
| 5G | RMB173.60 | In Stock |
|
| 25g | RMB639.20 | In Stock |
|
| 100g | RMB1999.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | >300 °C (dec.)(lit.) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | NH4OH 1 M: 50 mg/mL, clear to very faintly turbid, yellow to brown |
| form | powder |
| pka | pK1:2.5(+1) (25°C,μ=0.1) |
| color | White to Off-White |
| biological source | synthetic (organic) |
| BRN | 39814 |
| InChI | InChI=1/C10H13N5O4/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,6+/s3 |
| InChIKey | LZSCQUCOIRGCEJ-FPKZOZHISA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)C[C@@H]1O |&1:2,4,17,r| |
Description and Uses
2''-Deoxyguanosine is a purine nucleoside with diverse biological activities. It inhibits the clonogenic growth of HL-60 and K562 leukemia cells (IC50s = 80 and 100 μM, respectively). 2''-Deoxyguanosine inhibits the growth of MOLT-4 T cells and MGL-8 B cells by 99.8 and 68.3%, respectively, when used at a concentration of 50 μM. It increases the number of binucleated cells, a marker of inhibited cytokinesis, in A. sativum meristems. 2''-Deoxyguanosine (>1 μM) also induces relaxation of precontracted isolated bovine lingual artery.
2′-Deoxyguanosine monohydrate has been used in stromal cell purification. It has also been used for the quantification of whole cell dNTP (deoxyribonucleotide triphosphate).
